Protein name:
Collagen alpha-1(XVIII) chain ;
Alternative:
Endostatin ;
Organism:
COL18A1 (Homo sapiens).
General Annotation
Function:
Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling.
Subcellular Location:
Secreted
extracellular space
extracellular matrix
Protein Attributes:
50:
MAPYPCGCHI | LLLLFCCLAA | ARANLLNLNW | LWFNNEDTSH | AATTIPEPQG |
100:
PLPVQPTADT | TTHVTPRNGS | TEPATAPGSP | EPPSELLEDG | QDTPTSAESP |
150:
DAPEENIAGV | GAEILNVAKG | IRSFVQLWND | TVPTESLARA | ETLVLETPVG |
200:
PLALAGPSST | PQENGTTLWP | SRGIPSSPGA | HTTEAGTLPA | PTPSPPSLGR |
250:
PWAPLTGPSV | PPPSSGRASL | SSLLGGAPPW | GSLQDPDSQG | LSPAAAAPSQ |
300:
QLQRPDVRLR | TPLLHPLVMG | SLGKHAAPSA | FSSGLPGALS | QVAVTTLTRD |
350:
SGAWVSHVAN | SVGPGLANNS | ALLGADPEAP | AGRCLPLPPS | LPVCGHLGIS |
400:
RFWLPNHLHH | ESGEQVRAGA | RAWGGLLQTH | CHPFLAWFFC | LLLVPPCGSV |
450:
PPPAPPPCCQ | FCEALQDACW | SRLGGGRLPV | ACASLPTQED | GYCVLIGPAA |
500:
ERISEEVGLL | QLLGDPPPQQ | VTQTDDPDVG | LAYVFGPDAN | SGQVARYHFP |
550:
SLFFRDFSLL | FHIRPATEGP | GVLFAITDSA | QAMVLLGVKL | SGVQDGHQDI |
600:
SLLYTEPGAG | QTHTAASFRL | PAFVGQWTHL | ALSVAGGFVA | LYVDCEEFQR |
650:
MPLARSSRGL | ELEPGAGLFV | AQAGGADPDK | FQGVIAELKV | RRDPQVSPMH |
700:
CLDEEGDDSD | GASGDSGSGL | GDARELLREE | TGAALKPRLP | APPPVTTPPL |
750:
AGGSSTEDSR | SEEVEEQTTV | ASLGAQTLPG | SDSVSTWDGS | VRTPGGRVKE |
800:
GGLKGQKGEP | GVPGPPGRAG | PPGSPCLPGP | PGLPCPVSPL | GPAGPALQTV |
850:
PGPQGPPGPP | GRDGTPGRDG | EPGDPGEDGK | PGDTGPQGFP | GTPGDVGPKG |
900:
DKGDPGVGER | GPPGPQGPPG | PPGPSFRHDK | LTFIDMEGSG | FGGDLEALRG |
950:
PRGFPGPPGP | PGVPGLPGEP | GRFGVNSSDV | PGPAGLPGVP | GREGPPGFPG |
1000:
LPGPPGPPGR | EGPPGRTGQK | GSLGEAGAPG | HKGSKGAPGP | AGARGESGLA |
1050:
GAPGPAGPPG | PPGPPGPPGP | GLPAGFDDME | GSGGPFWSTA | RSADGPQGPP |
1100:
GLPGLKGDPG | VPGLPGAKGE | VGADGVPGFP | GLPGREGIAG | PQGPKGDRGS |
1150:
RGEKGDPGKD | GVGQPGLPGP | PGPPGPVVYV | SEQDGSVLSV | PGPEGRPGFA |
1200:
GFPGPAGPKG | NLGSKGERGS | PGPKGEKGEP | GSIFSPDGGA | LGPAQKGAKG |
1250:
EPGFRGPPGP | YGRPGYKGEI | GFPGRPGRPG | MNGLKGEKGE | PGDASLGFGM |
1300:
RGMPGPPGPP | GPPGPPGTPV | YDSNVFAESS | RPGPPGLPGN | QGPPGPKGAK |
1350:
GEVGPPGPPG | QFPFDFLQLE | AEMKGEKGDR | GDAGQKGERG | EPGGGGFFGS |
1400:
SLPGPPGPPG | PPGPRGYPGI | PGPKGESIRG | QPGPPGPQGP | PGIGYEGRQG |
1450:
PPGPPGPPGP | PSFPGPHRQT | ISVPGPPGPP | GPPGPPGTMG | ASSGVRLWAT |
1500:
RQAMLGQVHE | VPEGWLIFVA | EQEELYVRVQ | NGFRKVQLEA | RTPLPRGTDN |
1550:
EVAALQPPVV | QLHDSNPYPR | REHPHPTARP | WRADDILASP | PRLPEPQPYP |
1600:
GAPHHSSYVH | LRPARPTSPP | AHSHRDFQPV | LHLVALNSPL | SGGMRGIRGA |
1650:
DFQCFQQARA | VGLAGTFRAF | LSSRLQDLYS | IVRRADRAAV | PIVNLKDELL |
1700:
FPSWEALFSG | SEGPLKPGAR | IFSFDGKDVL | RHPTWPQKSV | WHGSDPNGRR |
1750:
LTESYCETWR | TEAPSATGQA | SSLLGGRLLG | QSAASCHHAY | IVLCIENSFM |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human Collagen alpha-1(XVIII) chain
ELISA Kit for Human Collagen alpha-1(XVIII) chain
CLIA Kit for Human Collagen alpha-1(XVIII) chain
CLIA Kit for Human Collagen alpha-1(XVIII) chain
Polyclonal Antibody for Human Collagen alpha-1(XVIII) chain
Polyclonal Antibody for Human Collagen alpha-1(XVIII) chain
Monoclonal Antibody for Human Collagen alpha-1(XVIII) chain
Monoclonal Antibody for Human Collagen alpha-1(XVIII) chain
Protein for Human Collagen alpha-1(XVIII) chain
Protein for Human Collagen alpha-1(XVIII) chain
R&D Technical Data
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Precision
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Recovery
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Linearity
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